AFFINIMIP® SPE Bisphenols
Ready-to-use kits AFFINIMIP® SPE Bisphenols analysing:
- More than 15 Bisphenol (A, S, E, F, etc.)
- In water, milk, canned foods, urine, plasma, blood, wine, beer, baby food, etc.
Bisphenol A is an endocrine disruptor that can mimic the body’s own hormones and may lead to negative health effects.
Regulatory measures
On June 2024, EU Member states agreed to ban Bisphenol A (BPA) on food contact materials (FCM) with a transition period of 18 to 36 months depending on the products.
The decision is based on a scientific assessment from the European Food Safety Authority (EFSA), which concluded that BPA had “potential harmful effects on the immune system”.
This ban will apply mainly to the use of BPA in packaging, such as the coating used on metal cans. The use of BPA in consumer articles such as reusable plastic drink bottles, water distribution coolers or other kitchenware will also be banned.
About our product
AFFINIMIP® SPE Bisphenols are selective solid phase extraction cartridges that selectively clean and concentrate Bisphenol A and closely related structures such as BADGE prior to analysis by chromatography (LC, GC…).
This kit is very powerful to target a large range of bisphenol analogs with high sensitivity.
Good to know: LABERCA, a French National Reference Laboratory (NRL) has published a peer-reviewed scientific article targeting 18 “BPA-like” compounds using AFFINIMIP®SPE Bisphenols with recovery yields higher than 90% for each molecule.
In this publication, the 18 bisphenol analogues analyzed were:
- Bisphenol B (BPB), bisphenol AP (BPAP), bisphenol AF (BPAF), bisphenol BP (BPBP), bisphenol C (BPC), bisphenol Cl2 (BPCl2), bisphenol E (BPE), bisphenol PH (BPPH),
- Bisphenol S (BPS), bisphenol F (BPF), [4,4′-dihydroxydiphenyl ether (DHDPE), bisphenol FL (BPFL), bisphenol Z (BPZ), biphenyl-4,4′-diol (BP4,4′), bisphenol M (BPM), bisphenol P (BPP), bis-2(hydroxyphenyl)methane (BIS2) and biphenyl-2,2′-diol (BP2,2′).
- Perfect clean-up system for trace analysis of Aflatoxins B1, B2, G1, G2
- High stability: it can be stored at room temperature for stability for years
- Easily automatable
- Ready-to-use kit with a very simple protocol to apply
- Compliant with European Commission Regulation (EC) 2023/915
Affinisep also provides strong support for implementing the method.
Booklet AFFINIMIP® SPE Bisphenols collects main useful information about :
- Regulations
- General protocols
- Advantages of using AFFINIMIP® SPE Bisphenols
- Application notes
For scientific articles on AFFINIMIP® SPE Bisphenols please click here (Literature).
Application Note AFFINIMIP®SPE Bisphenols for the total Bisphenol A determination in human urine
Human Urine
This application note describes a method to determine TOTAL Bisphenol A in Human urine. The combination of AFFINIMIP® SPE Bisphenols and LC-MS/MS enables the determination of very low concentration of Bisphenol A in urine.
Application note AFFINIMIP®SPE BISPHENOLS - COLA drinks
Cola drinks
This application note describes a method to determine Bisphenol A in Cola drinks. Recovery yields higher than 90% were obtained at concentration of 5ng/mL.
Application Note AFFINIMIP®SPE for the analysis of Bisphenol A in Beer at low concentrations
Beer matrices
This study describes the solid phase extraction of Bisphenol A from beer at low concentrations (1 and 2µg/L) using AFFINIMIP® SPE Bisphenols. HPLC analysis was performed with a flurescence detector. The results demonstrate the efficiency of the clean-up: high recovery yield (> 90%), a good repeatability and reproducibility were obtained.
Application Note AFFINIMIP®SPE Bisphenols - Red and white wines
Red and white wines
The determination of very low concentration (2µg/Kg) of Bisphenol A in Red and White Wines was carried out with a fluorescent detector after AFFINIMIP®SPE Bisphenols clean-up.
Application note AFFINIMIP®SPE BISPHENOLS - BISPHENOL A AND BADGE IN MILK
Bisphenol A and BADGE
This application note describes a method to determine Bisphenol A and BADGE in milk from plastic food packaging.
Application Note AFFINIMIP®SPE Bisphenols in Powdered Infant Formula at low concentrations
Powdered Infant Formula
This application note describes the analysis of very low concentration of BPA in powdered infant formula using AFFINIMIP®SPE Bisphenols cartridge. The method is perfectly suited for the quantification of Bisphenol A at very low concentration (2µg/L and 4µg/L), even using a fluorescence detector. The simple SPE procedure ensures mean recoveries > 95% and a very low relative standard deviation.
Application Note AFFINIMIP®SPE for the analysis of Bisphenol A in Infant Formula at low concentrations
Liquid Infant Formula
We demonstrate in this application note that a reliable quantification of Bisphenol A in liquid infant formula using fluorescence detection is possible, even at low concentrations(1 and 2µg/L). The use of AFFINIMIP®SPE Bisphenols enables to eliminate the tedious derivatization step required by gas chromatography.
Application note AFFINIMIP®SPE Bisphenols in Vegetable Puree
Vegetable Puree for Infants
This application note describes the analysis of very low concentration (3µg/kg and 24µg/kg) of BPA in vegetable puree for infant contained in a plastic food packaging using AFFINIMIP®SPE Bisphenols cartridge.
Application Note AFFINIMIP®SPE for the analysis of Bisphenol A from Canned Foods at low concentrations
Canned Foods
The tests were performed in canned peas and carrots and canned tuna and salmon. The results demonstrate the efficiency of the clean-up with fluorescence detection: high recovery yield (> 95%), a good repeatability and reproducibility were obtained in all the matrices.This method is also perfectly suitable for clean-up before GC-MS/MS or LC-MS/MS.